The second incarnation of West Side Park, which served as the home of the Chicago Orphans/Cubs franchise from 1893 through 1915, hosted three no-hitters:
| 1 | Walter Thornton |
|---|---|
| Chicago Orphans (NL) | |
| Sunday, August 21, 1898 (Second game of doubleheader) Chicago Orphans 2, Brooklyn Bridegrooms 0 West Side Park (Chicago) |
|
| 2 | Chick Fraser |
| Philadelphia Phillies (NL) | |
| Friday, September 18, 1903 (Second game of doubleheader) Philadelphia Phillies 10, Chicago Cubs 0 West Side Park (Chicago) |
|
| 3 | Christy Mathewson |
| New York Giants (NL) | |
| Tuesday, June 13, 1905 New York Giants 1, Chicago Cubs 0 West Side Park (Chicago) (His second of two no-hitters) |